![]() ![]() Pax7 + cells proliferate and then undergo terminal differentiation involving Myogenin accumulation and subsequent loss of Pax7 followed by elongation and fusion to repair fast muscle fibres. A swift immune response is followed by an increase in cells at the wound site, many of which express the muscle stem cell marker Pax7. Skeletal muscle with incision wounds rapidly regenerates both slow and fast muscle fibre types. Here we reveal stem/precursor cell diversity during wound repair in larval zebrafish somitic body muscle using time-lapse 3D confocal microscopy on reporter lines. Heterogeneity of stem cells or their niches is likely to influence tissue regeneration.
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